Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Avianca

The cheapest airline(s) flying from Mexico City to Santa Cruz de la Sierra is Avianca.

  • Avianca Avianca
  • LATAM Airlines Group SA LATAM Airlines Group SA
  • Copa Airlines Copa Airlines
  • Aerolineas Argentinas Aerolineas Argentinas
  • United Airlines United Airlines
Cheapest Month April

Travel Period: January 2025 - December 2025

The cheapest month(s) to fly from Mexico City to Santa Cruz de la Sierra is April.

  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
Cheapest Day of the Week Wednesday

The cheapest day(s) of the week to fly from Mexico City to Santa Cruz de la Sierra is Wednesday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Mon, 2 Dec, 2024

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  • Availability
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  • 18:45 MEX
    11:35 VVI
    14Hrs, 50m 1 Stop (GRU)
  • MEXMexico City Juarez International Airport 18:45 - VVI 11:35 14h 50m 1 Stop (GRU) Sao Paulo
  • MEXMexico City Juarez International Airport 18:45
    GRUSao Paulo Guarulhos Intl Airport 09:30
  • GRUSao Paulo Guarulhos Intl Airport 07:35
    VVISanta Cruz Viru Viru International Airport 11:35
  • 14h 50m (1h 55m)
  • 1 Stop GRU · Sao Paulo 1h 55m
  • Aeromexico (AM 14)Boeing 787 8
    Gol Transportes Aéreos (G3 7714)Boeing 737 Max 8 Passenger
  • Aeromexico (AM 14)
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 18:45 MEX
    11:35 VVI
    14Hrs, 50m 1 Stop (GRU)
  • MEXMexico City Juarez International Airport 18:45 - VVI 11:35 14h 50m 1 Stop (GRU) Sao Paulo
  • MEXMexico City Juarez International Airport 18:45
    GRUSao Paulo Guarulhos Intl Airport 09:30
  • GRUSao Paulo Guarulhos Intl Airport 07:35
    VVISanta Cruz Viru Viru International Airport 11:35
  • 14h 50m (1h 55m)
  • 1 Stop GRU · Sao Paulo 1h 55m
  • Aeromexico (AM 14)Boeing 787 9
    Gol Transportes Aéreos (G3 7714)Boeing 737 Max 8 Passenger
  • Aeromexico (AM 14)
    • M
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  • 05:55 MEX
    22:10 VVI
    14Hrs, 15m 1 Stop (PTY)
  • MEXMexico City Juarez International Airport 05:55 - VVI 22:10 14h 15m 1 Stop (PTY) Panama City
  • MEXMexico City Juarez International Airport 05:55
    PTYPanama City Tocumen International Airport 16:04
  • PTYPanama City Tocumen International Airport 10:41
    VVISanta Cruz Viru Viru International Airport 22:10
  • 14h 15m (5h 23m)
  • 1 Stop PTY · Panama City 5h 23m
  • Copa Airlines (CM 195)Boeing 737 800
    Copa Airlines (CM 127)Boeing 737 800
  • Copa Airlines (CM 195)
    • -
    • -
    • -
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    • -
  • 05:55 MEX
    22:10 VVI
    14Hrs, 15m 1 Stop (PTY)
  • MEXMexico City Juarez International Airport 05:55 - VVI 22:10 14h 15m 1 Stop (PTY) Panama City
  • MEXMexico City Juarez International Airport 05:55
    PTYPanama City Tocumen International Airport 16:04
  • PTYPanama City Tocumen International Airport 10:41
    VVISanta Cruz Viru Viru International Airport 22:10
  • 14h 15m (5h 23m)
  • 1 Stop PTY · Panama City 5h 23m
  • Copa Airlines (CM 195)Boeing 737 Max 9 Passenger
    Copa Airlines (CM 127)Boeing 737 800
  • Copa Airlines (CM 195)
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  • 05:55 MEX
    22:10 VVI
    14Hrs, 15m 1 Stop (PTY)
  • MEXMexico City Juarez International Airport 05:55 - VVI 22:10 14h 15m 1 Stop (PTY) Panama City
  • MEXMexico City Juarez International Airport 05:55
    PTYPanama City Tocumen International Airport 16:04
  • PTYPanama City Tocumen International Airport 10:41
    VVISanta Cruz Viru Viru International Airport 22:10
  • 14h 15m (5h 23m)
  • 1 Stop PTY · Panama City 5h 23m
  • Copa Airlines (CM 195)Boeing 737 800
    Copa Airlines (CM 127)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 195)
    • -
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    • -
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  • 09:25 MEX
    22:10 VVI
    10Hrs, 45m 1 Stop (PTY)
  • MEXMexico City Juarez International Airport 09:25 - VVI 22:10 10h 45m 1 Stop (PTY) Panama City
  • MEXMexico City Juarez International Airport 09:25
    PTYPanama City Tocumen International Airport 16:04
  • PTYPanama City Tocumen International Airport 14:15
    VVISanta Cruz Viru Viru International Airport 22:10
  • 10h 45m (1h 49m)
  • 1 Stop PTY · Panama City 1h 49m
  • Copa Airlines (CM 137)Boeing 737 800
    Copa Airlines (CM 127)Boeing 737 800
  • Copa Airlines (CM 137)
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    • S
  • 09:25 MEX
    22:10 VVI
    10Hrs, 45m 1 Stop (PTY)
  • MEXMexico City Juarez International Airport 09:25 - VVI 22:10 10h 45m 1 Stop (PTY) Panama City
  • MEXMexico City Juarez International Airport 09:25
    PTYPanama City Tocumen International Airport 16:04
  • PTYPanama City Tocumen International Airport 14:15
    VVISanta Cruz Viru Viru International Airport 22:10
  • 10h 45m (1h 49m)
  • 1 Stop PTY · Panama City 1h 49m
  • Copa Airlines (CM 137)Boeing 737 800
    Copa Airlines (CM 127)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 137)
    • -
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    • -
    • -
    • F
    • -
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  • 13:10 MEX
    03:36 VVI
    12Hrs, 26m 1 Stop (PTY)
  • MEXMexico City Juarez International Airport 13:10 - VVI 03:36 12h 26m 1 Stop (PTY) Panama City
  • MEXMexico City Juarez International Airport 13:10
    PTYPanama City Tocumen International Airport 21:43
  • PTYPanama City Tocumen International Airport 17:55
    VVISanta Cruz Viru Viru International Airport 03:36
  • 12h 26m (3h 48m)
  • 1 Stop PTY · Panama City 3h 48m
  • Copa Airlines (CM 121)Boeing 737 800
    Copa Airlines (CM 221)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 121)
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  • 13:10 MEX
    03:36 VVI
    12Hrs, 26m 1 Stop (PTY)
  • MEXMexico City Juarez International Airport 13:10 - VVI 03:36 12h 26m 1 Stop (PTY) Panama City
  • MEXMexico City Juarez International Airport 13:10
    PTYPanama City Tocumen International Airport 21:43
  • PTYPanama City Tocumen International Airport 17:55
    VVISanta Cruz Viru Viru International Airport 03:36
  • 12h 26m (3h 48m)
  • 1 Stop PTY · Panama City 3h 48m
  • Copa Airlines (CM 121)Boeing 737 800
    Copa Airlines (CM 221)Boeing 737 800
  • Copa Airlines (CM 121)
    • -
    • -
    • -
    • -
    • F
    • -
    • -
  • 13:50 MEX
    02:00 VVI
    10Hrs, 10m 1 Stop (BOG)
  • MEXMexico City Juarez International Airport 13:50 - VVI 02:00 10h 10m 1 Stop (BOG) Bogota
  • MEXMexico City Juarez International Airport 13:50
    BOGBogota Airport 20:55
  • BOGBogota Airport 19:20
    VVISanta Cruz Viru Viru International Airport 02:00
  • 10h 10m (1h 35m)
  • 1 Stop BOG · Bogota 1h 35m
  • Avianca (AV 73)Airbus A320 Neo
    Avianca (AV 8382)Airbus
  • Avianca (AV 73)
    • M
    • -
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  • 13:50 MEX
    02:00 VVI
    10Hrs, 10m 1 Stop (BOG)
  • MEXMexico City Juarez International Airport 13:50 - VVI 02:00 10h 10m 1 Stop (BOG) Bogota
  • MEXMexico City Juarez International Airport 13:50
    BOGBogota Airport 20:55
  • BOGBogota Airport 19:20
    VVISanta Cruz Viru Viru International Airport 02:00
  • 10h 10m (1h 35m)
  • 1 Stop BOG · Bogota 1h 35m
  • Avianca (AV 73)Airbus
    Avianca (AV 8382)Airbus
  • Avianca (AV 73)
    • -
    • -
    • -
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  • 13:50 MEX
    02:00 VVI
    10Hrs, 10m 1 Stop (BOG)
  • MEXMexico City Juarez International Airport 13:50 - VVI 02:00 10h 10m 1 Stop (BOG) Bogota
  • MEXMexico City Juarez International Airport 13:50
    BOGBogota Airport 20:55
  • BOGBogota Airport 19:20
    VVISanta Cruz Viru Viru International Airport 02:00
  • 10h 10m (1h 35m)
  • 1 Stop BOG · Bogota 1h 35m
  • Avianca (AV 73)Airbus A320 Neo
    Avianca (AV 8382)Airbus
  • Avianca (AV 73)
    • -
    • -
    • -
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    • -
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  • 14:46 NLU
    03:36 VVI
    10Hrs, 50m 1 Stop (PTY)
  • NLU 14:46 - VVI 03:36 10h 50m 1 Stop (PTY) Panama City
  • NLU 14:46
    PTYPanama City Tocumen International Airport 21:43
  • PTYPanama City Tocumen International Airport 19:31
    VVISanta Cruz Viru Viru International Airport 03:36
  • 10h 50m (2h 12m)
  • 1 Stop PTY · Panama City 2h 12m
  • Copa Airlines (CM 117)Boeing 737 800
    Copa Airlines (CM 221)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 117)
    • M
    • -
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  • 15:30 MEX
    03:36 VVI
    10Hrs, 06m 1 Stop (PTY)
  • MEXMexico City Juarez International Airport 15:30 - VVI 03:36 10h 06m 1 Stop (PTY) Panama City
  • MEXMexico City Juarez International Airport 15:30
    PTYPanama City Tocumen International Airport 21:43
  • PTYPanama City Tocumen International Airport 20:16
    VVISanta Cruz Viru Viru International Airport 03:36
  • 10h 06m (1h 27m)
  • 1 Stop PTY · Panama City 1h 27m
  • Copa Airlines (CM 135)Boeing 737 800
    Copa Airlines (CM 221)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 135)
    • M
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  • 15:30 MEX
    03:36 VVI
    10Hrs, 06m 1 Stop (PTY)
  • MEXMexico City Juarez International Airport 15:30 - VVI 03:36 10h 06m 1 Stop (PTY) Panama City
  • MEXMexico City Juarez International Airport 15:30
    PTYPanama City Tocumen International Airport 21:43
  • PTYPanama City Tocumen International Airport 20:16
    VVISanta Cruz Viru Viru International Airport 03:36
  • 10h 06m (1h 27m)
  • 1 Stop PTY · Panama City 1h 27m
  • Copa Airlines (CM 135)Boeing 737 800
    Copa Airlines (CM 221)Boeing 737 800
  • Copa Airlines (CM 135)
    • -
    • -
    • -
    • -
    • F
    • -
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  • 16:05 MEX
    04:45 VVI
    10Hrs, 40m 1 Stop (LIM)
  • MEXMexico City Juarez International Airport 16:05 - VVI 04:45 10h 40m 1 Stop (LIM) Lima
  • MEXMexico City Juarez International Airport 16:05
    LIMLima Airport 01:00
  • LIMLima Airport 22:40
    VVISanta Cruz Viru Viru International Airport 04:45
  • 10h 40m (2h 20m)
  • 1 Stop LIM · Lima 2h 20m
  • LATAM Airlines Group SA (LA 2471)Airbus
    LATAM Airlines Group SA (LA 2406)Airbus
  • LATAM Airlines Group SA (LA 2471)
    • M
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What’s the most popular airline flying from Mexico City to Santa Cruz de la Sierra?

The most popular airline flying from Mexico City to Santa Cruz de la Sierra is LATAM Airlines Group SA. Find the latest flight deals on Wego.

How far is Santa Cruz de la Sierra from Mexico City?

The flight distance between Mexico City and Santa Cruz de la Sierra is 5708km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 05:55. The last flight of the day departs at 18:45. See the full list of flight times on Wego.